Services

Consulting

We focus on regulatory compliance also laboratory management financial management and operational efficiency’s These services aim to help laboratory organizations improve their overall performance, maintain compliance with regulations, and ensure a safe working environment for laboratory personnel.

As far as safety is concerned, the top priority in a clinical laboratory is to ensure the safety of both employees and patients. This can be achieved by implementing and following standard operating procedures, providing proper training and personal protective equipment, conducting regular safety inspections, and maintaining a clean and organized work environment. Additionally, adhering to regulations and guidelines set by organizations such as OSHA, CLIA, and CAP can help ensure a safe laboratory environment.

Project management

This includes communication with clients to understand their requirements, setting up a project plan, overseeing the execution of tasks, ensuring that all quality standards are met, and providing regular updates to clients on the progress of the project. Our team is well-equipped to handle projects of any size and complexity, and we are committed to delivering results that meet or exceed our clients’ expectations.

We use advanced project management tools to keep track of project progress, resources, and budgets. Our project managers work closely with our laboratory technicians to ensure that the project is executed efficiently and that the specimens are processed with precision. We also have a robust quality control system in place to ensure that the final products meet our high standards.

At DRL, we understand the importance of delivering projects on time, and we are committed to meeting our clients’ deadlines. We are dedicated to providing exceptional customer service and strive to establish long-lasting partnerships with our clients. Our goal is to be a trusted and reliable partner for all of your project management needs.

Bio banking

With our biobanking solutions, you can be confident that your samples are stored and managed in a secure, controlled environment that meets the highest standards for quality and safety. Our biobanking systems allow for easy sample tracking, enabling you to quickly locate and access the samples you need for your research or diagnostic needs. Our biobanking services include sample preparation and automation, ensuring that your samples are ready for use when you need them.

We understand the importance of protecting and preserving your samples, and our biobanking equipment is designed to provide long-term stability and protection from contamination and degradation. Whether you are storing blood, tissue, or other biological specimens, our biobanking solutions are the ideal choice for your laboratory.

With our biobanking services, you can focus on your research or diagnostic needs, confident that your samples are stored and managed with the highest level of care and professionalism. We are committed to helping you achieve your scientific and clinical goals, and we stand behind our products and services with a team of experienced biobanking professionals. So why wait? Invest in our biobanking solutions today and start making the most of your sample collection and management process.

Area of experties

  • Oncology – Solid Tumors (all types)
  • Oncology – Hematology (AML, MM, etc.)
  • Autoimmune diseases (RA, SLE, etc.)
  • Healthy donors
  • Cardiovascular conditions (MI, ACS, etc.)
  • Gastroenterology diseases (Ulcerative colitis, Crohn`s disease, etc)
  • Pulmonology diseases (Asthma, COPD, etc.)
  • Infectious disease ( HCV, HBV, HIV etc)
  • Neurological diseases (PD, AD, MS, etc.)
  • Metabolic disorders (Diabetes, Hypothyroidism, etc.)
  • Inherited conditions (Cystic Fibrosis)

Management service

Diagnostic Research Laboratory, Inc., provides annotated human biospecimens for biomedical research. These biospecimens could be acquired in biobank or in the process of customized prospective procurement.

In particular our service includes:

  • Estimated accrual rate based on your collection needs
  • Evaluation of the project feasibility, specifications and protocols
  • Development of the project specifications and special protocols (if requested)
  • Management of IRB/IEC submission process
  • Selection and qualification of the clinical sites
  • Project implementation and monitoring at the clinical site(s)
  • Quality control of the collected samples
  • Organization of the sample’s storage and delivery to the client
  • Conducting of internal audit of the clinical sites

Laboratory services

Diagnostic Research Laboratory is proud to offer optional histology slide scanning and image analysis services with well-characterized clinical information:

  • High-definition, brightfield, scanning with 3DHISTECH
  • 20x or 40x magnification
  • Image analysis (H&E, IHC, CISH, other visible stains) and quantitation of cancer biomarkers (e.g., ER, PR, Ki67, Her2, PD-L1)
ISOLATION OF PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) AND BONE MARROW MONONUCLEAR CELLS (BMMCS)

PBMCs or BMMCs can be isolated from whole blood or bone marrow aspirate respectively. Isolated cells are cryopreserved and stored in liquid nitrogen vapor. Each vial of viable PBMCs or BMMCs contains at least 5 x 10E6 cells.

ISOLATION OF PLASMA AND SERUM FROM PERIPHERAL BLOOD

We can isolate up to 10 – 15 ml plasma or serum per donor per blood draw, using our standard SOP or customized protocol. Obtained plasma and serum is aliquoted and cryopreserved as described in the protocol.

ISOLATION OF VIABLE CELLS FROM DISSOCIATED FRESH TISSUE

Isolation of viable cells from dissociated fresh tissue can be performed, including isolation of tumor-infiltrating lymphocytes (TILs) from fresh tumor specimens.

 
DNA AND RNA SPECIMENS

DNA and RNA specimens can be isolated from fresh tissue, FF tissue, FFPE tissue and peripheral blood procured from patients and normal donors.

SCREENING FOR GENE MUTATIONS

DNA and RNA specimens can be isolated from fresh tissue, FF tissue, FFPE tissue and peripheral blood procured from patients and normal donors.

SCREENING FOR GENE MUTATIONS

Subcontracted laboratories of Diagnostic Research Laboratory provide a wide offering of mutation screening using real-time PCR.

Diagnostic Research Laboratory screens for the following gene mutations:

  • Breast Cancer KRAS, BRCA, PI3K
  • Lung cancer – EGFR, KRAS, EML4-ALK
  • Colorectal cancer – KRAS, BRAF, NRAS, PIK3CA
  • Melanoma – BRAF, NRAS
  • Leukemia – BCR-ABL, PML-RARA, E2A-PBX1, AML1-ETO, MLL-AF4, TEL-AML1

Other types of cancer could be screened upon request of the client.