DRL logo
preclinical research partner

Human-Relevant Models.
Real Answers — Faster.

DRL connects pharma and biotech R&D teams directly to IND-ready data through wide portfolio of products, including organoids, cell lines and fresh human samples.

What We Can Do For You

Move Beyond Immortalized Cell Lines

DRL provides boutique biospecimen procurement, patient-derived primary 2D/3D models development, and integrated validation — so you can confirm mechanism of action, test combination strategies, and
uncover resistance pathways.
Primary Derived Cells
Patient-derived, low-passage tumor cell lines, CAFs, TILs, and normal fibroblasts. Authenticated, mycoplasma-free, shipped ready for assay. Available across 30+ cancer types with matched metadata.
Patient-Derived 3D Tumor Models
Fresh tumor-derived 3D cultures that maintain original architecture and heterogeneity. Better drug-response prediction than 2D or PDX. Screen compounds in days, not months.
Biospecimens (including rare nosologies)
50,000+ well-characterized cases. FFPE, fresh, frozen tissue, blood, biofluids, and dissociated single-cell mixes. Sourced from 33 hospitals and 18 clinics with full clinical metadata and consent for commercial use.
Assay Services (GLP-aligned)
Drug screening, functional validation, immune profiling, and molecular / assay support—developed for reproducibility and decision-grade outputs.
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Scientific and implementation Support
Our scientists help clients to integrate 3D tumor models into their R&D pipelines, and provide all necessary support and expertise.
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In development

LelekaBio™ - Predictive Onclology Platform

What is LeleKaBio™?

An upcoming predictive oncology platform built on real human biology, integrating high-quality patient-derived 3D tumor models with AI to simulate drug response and resistance before clinical trials.
Platform components (available now)
Patient-derived 3D tumor models and multi-omics profiling services.
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LelekaBio™ Digital Twin Engine (in development)
AI-powered prediction of tumor drug response. Integrates gene and RNA
expression, CNVs, and clinical metadata to identify resistance patterns and stratification opportunities.
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why drl?

Models Built Around Your Study, Not the Other Way

Custom Models,
no Compromises

Customizable 3D tumor models and clinical trial materials designed to match your specific cancer type, patient genetics, and drug target — not off-the-shelf compromises.

We Own the Full Cycle

From sample collection through processing, QC, and delivery — no third-party handoffs, no black boxes. You have full visibility into every step.

Labs on Both Sides
of the Atlantic

US and European laboratory network ensures redundancy, faster turnaround, competitive pricing, and access to tissue types that are scarce in a single market.

Quality, Traceability, and IP Protection by Design

DRL provides chain-of-custody, end-to-end traceability, and ethical sourcing that positions this supplier as suitable for IND-ready regulatory work. Clients own their data, models, and IP. No restricted-use licensing surprises.

drl end-to-end

DRL’s Workflow: From Tissue to Decisions, End-to-End

Define

Study need, indication, biomarkers, endpoints, timelines

Procure

Banked/prospective biospecimen collection, QC + metadata

Generate

Primary cells, 3D organoids, culture systems

Validate and Learn

Drug screening, functional assays, omics, biomarker insights

our partners

Used by global pharma and oncology biotech teams for translational research, efficacy testing, and biomarker studies.
Partners: Regeneration, Merck, Roche, Bristol Myers Squibb, Sana, Bio rad, Personalis, Veracyte, abbvie

33+

hospitals

18+

clinics

26+

pharma teams

30+

cancer types
Alexander Adler - Principal Scientist at Regeneron
“DRL is committed to procuring high quality human specimens in a timely manner. Their scientists are engaged and proactive at addressing the needs of their clients. We are glad we entrusted DRL with helping us advance our target validation projects and will continue to use their professional services in the future.”
Alexander Adler
Principal Scientist @ Regeneron Pharmaceuticals, Inc.
John M.Lyle PhD VP Assay Development
"We prefer to work with DRL for our sample acquisition needs as they provide us with high quality materials in a timely manner. They are agile and able to adapt to our varied needs across projects and requests for different levels of documentation. They respond incredibly quickly and thoroughly to any queries. They complete their collections within projected time frames. Unfortunately for the space as a whole, these observations are in contrast to most vendors. In summary, they are a pleasure to work with and have become my preferred vendor."
John M. Lyle, PhD
VP Assay Development R&D @ Personalis
Q & A
collaboration
ready to ACCELerate your program?

Ready to De-Risk Your Next Decision?

Tell us your indication, disease type, and preferred model type.
We’ll match the right DRL product and study plan to your timeline.
DRL logo
Contract research organization, which provides solutions for pharma and diagnostics companies, including consulting, cancer models development, and various assays for drug development.
contact
28047 Dorothy Drive, #204,
Agoura Hills, CA 91301, USA
Call: +1 442-224-3375
E-mail: Info@drlus.com
©2026 DRL US. All Rights Reserved.

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Learn how LelekaBio can help you make better decisions with biology-first AI.