Address: 4055 Oceanside BLVD,Oceanside, CA, 92056
Call us today: +1 442-224-3375
Well-characterized high-quality human tissues and biofluids: more than 50,000 cases, including 100,000 images of the tumor.
BioBank of more than 30,000 oncology cases.
Biospecimens with specific molecular characteristics can be requested.
Low-passage patient-derived material preserves primary cell features and provides more reliable results.
Robust and easy to use for preclinical trials and research.
Better evaluation, in an early stage, of which drugs are effective compared to 2D cell line models.
Faster development and less expensive compared to patient-derived xenograft (PDX) models.
Variety of unique cells derived from fresh samples supplemented with robust patient information. We offer a wide variety of unique human primary cancer cell lines derived from tumors and surrounding tissues. We have access to various fresh tissue specimens from core biopsies, pleural effusions, and resections which reflect the tumor's natural microenvironment and preserve specific crosstalk between healthy and cancer cells. All our samples are traceable back to the patient and can be supplied with relevant information including demographics and medical history.
Freshly isolated and frozen at the early passage to preserve unique in vivo tumor features. Our primary cells are freshly isolated using well-established standardized enzymatic digest and mechanical isolation protocols and maintained for culture in vitro. We offer robust primary cell cultures at the early passage when the cells more closely recapitulate the physiological state of in vivo tumors and therefore allow the generation of the most biologically relevant data.
Advantage over immortalized cells. Our cells offer an advantage in preclinical and discovery oncology research compared to widely used immortalized cells, which commonly carry gross mutations and chromosomal abnormalities that can attribute to changed cell behavior and limited usefulness in studying specific cancer mechanisms.
We are still working on our catalog of primary cells, please send your inquiry to us directly using our contact form.
Step up your in vitro drug testing using our 3D cell culture models. Our group of highly qualified and experienced scientists offers the generation of custom 3D cellular models for your research.
We culture human primary cancer cells obtained from the donor’s tissues in multicellular, three-dimensional structures, more closely recapitulating the architecture of the parental tissue than is possible in the 2D adherent cell cultures.
Spheroid models can better predict the drug response and drug resistance as the morphology and polarity of the cells are maintained, and they imitate in vivo-like cellular crosstalk and interactions with the environment.
Therefore, primary cancer cells cultivated in the form of spheroids preserve the closest similarity to the in vivo tumor cells when studying gene expression, signaling, and metabolism.
Diagnostic Research Laboratory (DRL) offers a range of innovative products and services to fast-track drug development, including:
Innovative: closely mimic the complex structure and functionality of human organs.
Sophisticated: better insight into human development and disease.
Reliable: confirmed by fluorescence and luminescence assays.
Efficient: preserve data integrity.
Fast evaluation of drug efficiency and safety before clinical trials.
Easier to determine dosage.
Saved lives of healthy people.
Access to low-cost medical facilities overseas.
In compliance with legal and ethical standards