Cell Viability, Proliferation, and Apoptosis

Applications:
  • Screen potential anticancer compounds for cytotoxicity to identify promising therapeutic candidates.
  • Assess cell proliferation rates to understand the effects of treatments on cancer cell growth.
  • Evaluate apoptosis induction by therapeutic agents to determine their effectiveness.
  • Monitor metabolic activity as an indicator of cell health and viability.
Samples:
  • Primary cancer cells and 3D organoids.
Assays:
  • Cell viability assays (MTT, MTS, CellTiter Glo):
  • Measure cell viability and metabolic activity using colorimetric or luminescent readouts.
  • Apoptosis assays (Annexin V, PI staining, Cl Caspase measurement, TUNEL):
  • Detect and quantify apoptotic cells using flow cytometry, microscopy, or plate-based assays.
  • High-throughput proliferation assays (MTT, MTS):
  • Quantify cell proliferation rates using colorimetric assays.
  • Cell cycle assessment:
  • Analyzes cell cycle distribution using flow cytometry.
  • Metabolic assays (CellTiter Glo):
  • Measure cellular ATP levels as an indicator of metabolic activity.
  • Luminex® multiplex assay:
  • Simultaneously measures multiple proteins in a single sample using bead-based technology.
Contract research organization, which provides solutions for pharma and diagnostics companies, including consulting, cancer models development, and various assays for drug development.
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