Develop and optimize cell-based assays for high-throughput drug screening.
Perform high-throughput screening to identify lead compounds with anticancer activity.
Validate hits through secondary assays and mechanistic studies to confirm their potential.
Discover new therapeutic candidates for cancer treatment by screening compound libraries.
Samples:
Primary cancer cells and 3D organoids.
Assays:
Cell-based assay development:
Design and optimize assays to evaluate compound effects on cell viability, proliferation, and function.
High-throughput screening of compounds of interest:
Test large compound libraries for anticancer activity using automated systems.
Hit identification and validation:
Confirm and characterize hits from primary screens using secondary assays and mechanistic studies.
Contract research organization, which provides solutions for pharma and diagnostics companies, including consulting, cancer models development, and various assays for drug development.