Evaluate the invasive potential of cancer cells to understand mechanisms of metastasis.
Assess the effect of drugs on cell migration and invasion to develop anti-metastatic therapies.
Study the molecular mechanisms underlying cancer cell invasiveness and metastasis.
Samples:
Primary cancer cells.
Assays:
Matrigel invasion assay:
Measures the ability of cancer cells to invade through a Matrigel matrix, mimicking the extracellular environment.
Scratch migration assay:
Assesses cell migration by creating a “scratch” in a cell monolayer and measuring the rate of wound closure.
Contract research organization, which provides solutions for pharma and diagnostics companies, including consulting, cancer models development, and various assays for drug development.
